AIB Labs Facilities
Services provided by each AIB Labs Facility are summarised below:
- Conducts high-throughput analysis of differential gene expression.
- Expertise in printing microarrays, probe generation, scanning of microarrays and data analysis.
Website: http://www.microarray.adelaide.edu.au/
- Offers a broad range of advanced microscopy and microanalysis instrumentation for material and biological sciences.
- Provide training and expert assistance in sample preparation and operation.
- Consulting services.
Website: http://www.adelaide.edu.au/microscopy/
- Identification and characterization of proteins and peptides using 2D and free electrophoresis and various state of the art mass spectrometers i.e. Q-TOF, Maldi-TOF/TOF, ion trap.
Website: http://www.adelaide.edu.au/mbs/proteomics
- An advanced, high capacity, intensive aquarium system developed for the maintenance of mutant and transgenic lines of Zebrafish.
- The facility offers complete animal housing solutions with high quality husbandry standards, as well as access to brood stock fish for production of fertilized embryos.
Website: http://www.adelaide.edu.au/mbs/zebrafish/
- Plant DNA extraction and PCR-product analytical services.
- Controlled environment plant growth / stress facilities.
- DNA archiving and distribution facility.
Website: http://www.agrf.org.au/
- Adelaide's Metabolomics Facility draws on the expertise of the Australian Wine Research Institute and Metabolomics Australia to provide researchers with the technology and expertise to analyse organisms at a metabolic level.
- The facility's research platforms include gas chromatography, liquid chromatography, mass spectrometry and bioinformatics tools.
- The technology can be used for drug discovery and development as well as plant and microbial research.
Website: http://www.awri.com.au/research_and_development/ahead_of_the_game/metabolomics/
- Allows researchers direct access to a range of technologies with the capacity to undertake a range of biophysical characterisations to support basic research, drug development and therapeutic programs.
- The facility will enable protein thermodynamic, kinetic, structural, stability and molecular interaction studies to facilitate drug target identification, as well as drug development/optimisation, where the interaction with protein targets is critical for efficacy.
- The facility will be housed within a newly refurbished laboratory, due for completion in March 2009.
Email: emma.parkinson-lawrence@unisa.edu.au
- Peptide and protein ID and analysis by mass spectrometry.
- Compound analysis and structural analysis by tandem mass spectrometry.
- Stable isotope ratio analysis.
- Biomolecular interactions analysis.
Website: http://www.flinders.edu.au/flinders-analytical/
- Wide range of advanced microscopy and associated 3D image processing and reconstruction program with a focus on imaging of biological materials.
- Training and protocols can be provided for sample preparation, operation and data image reconstruction.
Website: http://som.flinders.edu.au/FUSA/Anatomy/FMIAF/FMIAFHome.htm
Provides a range of services for companies wishing to establish the safety and efficacy of new drugs or devices:
- Range finding and repeat dose studies.
- Pharmacokinetic studies.
- Surgical facilties for large and small animals.
- Analytical studies.
- Consulting services.
For more information click here.
- Establishment of monoclonal antibodies-secreting hybridoma cell lines.
- Monoclonal antibody production.
Website: http://www.adelaide.edu.au/mbs/mabsa
- Small (1L, 100L) to large scale (1000L) fermentation for modelling industrial fermentations for wine and brewing industries.
Website:
http://agwine.adelaide.edu.au/wine/facilities/msff/
- The South Australian Research and Development Institute (SARDI) Gene Expression and Genotyping Facility is equipped with one of the first BioMark real-time PCR systems.
- The BioMark offers significant savings on real-time PCR reagents and eliminates the need for complex and time consuming liquid handling robotic procedures.
- The BioMark performs 2304 simultaneous PCR assays per run as well as digital PCR.
- The facility is available to trained users and a range of DNA-based services can also be offered to academic researchers and biotechnology companies.
For more information email nattrass.greg@saugov.sa.gov.au
Provides a range of functional biomarkers based on novel stable isotope probes for assessment of gut and other organ function e.g liver, pancreas.
These functional tests are not invasive and utilise easily collectable breath, urine, saliva etc. as the samples for analysis. Applications for these tests include:
- Rapid assessment of new nutritional and functional foods and supplements.
- Use in human clinical trials for fast tracking drug discovery.
- Use as diagnostics in clinical testing.
- Application to existing and new preclinical animal models.
- Potential to include these functional biomarkers to value add to preclinical and clinical trials.
Email:
ross.butler@unisa.edu.au
Provides pyrosequencing technologies for research related to the impact of gene-environment interactions on embryological and fetal development, regulation of tissue growth and differentiation in early and later life, nutrigenomics and pharmacogenomics as well as assessment of allele frequency and genetic variation, DNA mutation detection, sequence analysis and microbial typing.
Website: http://www.adelaide.edu.au/saef
Develops and applies advanced spectroscopic and interfacial characterisation techniques to support biotechnology R&D, product development and QA.
Website: http://www.unisa.edu.au/iwri/facilities/aiblabs.asp
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